Hydrogen, highly valued for its pristine cleanliness and remarkable efficiency as an emerging energy source, is anticipated to ascend to a preeminent status within the forthcoming energy landscape. Electrocatalytic water splitting is considered a pivotal, eco-friendly, and sustainable strategy for hydrogen production. The substantial energy consumption stemming from oxygen evolution side reactions significantly impedes the commercial viability of water electrolysis. Consequently, the pursuit of a cost-effective and efficacious oxygen evolution reaction (OER) catalyst stands as an imperative strategy for realizing hydrogen production via water electrolysis. Layered metal oxides, owing to their robust anisotropic properties, versatile adjustability, and extensive surface area, have emerged as suitable candidates for OER catalysts. However, owing to the distinctive attributes of layered metal oxides, ongoing investigations into these materials are slightly fragmented, lacking universal consensus. This article comprehensively surveys the recent advancements in layered metal oxide-based OER catalysts, categorized into single metal oxides, alkali cobalt oxides, perovskites, and miscellaneous metal oxides. Initially, the main OER intermediate reaction steps of layered metal oxides are scrutinized. Subsequently, the design, mechanism, and application of several pivotal layered metal oxides in the OER are systematically delineated. Finally, a summary is provided, alongside the proposal of future research trajectories and challenges encountered by layered metal oxides, with the aspiration that this paper may serve as a valuable reference for scholars in the field.