We present a case of hereditary multiple exostoses with malignant transformation to chondrosarcoma in a woman complaining of enlargement and pain in the right thigh. Hereditary multiple exostoses is a rare genetic disorder characterized by multiple osteochondromas. Malignant transformation to chondrosarcoma of a pre-existing osteochondroma is a possible significant manifestation of this hereditary syndrome. Imaging modalities such as X-ray, Ultrasound, and computed tomography play a crucial role in the diagnosis and management of these patients, as described in this case.
Keywords: Bone disorders; Chondrosarcoma; Diagnostic imaging; Exostosis; Hereditary multiple exostoses; Osteochondromas.
© 2024 The Authors. Published by Elsevier Inc. on behalf of University of Washington.