Diagnosis and treatment of peritoneal dialysis associated mycotic peritonitis caused by Aspergillus fumigatus infection

Dan Zhang; Guofeng Mao; Meichun Liang; Guiqin Sun; Debao Yu

doi:10.1016/j.mmcr.2024.100651

Diagnosis and treatment of peritoneal dialysis associated mycotic peritonitis caused by Aspergillus fumigatus infection

Med Mycol Case Rep. 2024 May 1:44:100651. doi: 10.1016/j.mmcr.2024.100651. eCollection 2024 Jun.

Authors

Dan Zhang¹, Guofeng Mao¹, Meichun Liang¹, Guiqin Sun², Debao Yu¹

Affiliations

¹ Department of Clinical Laboratory Center, Shaoxing People's Hospital, Shaoxing, 312000, PR China.
² School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, 310053, PR China.

Abstract

Aspergillus peritonitis is a rare but highly severe complication of peritoneal dialysis with a high mortality rate. We report a case of Aspergillus fumigatus peritonitis. Despite early removal of the catheter and oral voriconazole antifungal treatment for 3 weeks, the treatment effect was unsatisfactory, resulting in prolonged hospital stay and affecting the patient's quality of life. After switching to liposomalAmphotericin B, inflammation indicators rapidly decreased and infection was controlled. Liposomalamphotericin B provides an option for treatment of Aspergillus peritonitis.

Keywords: Aspergillus peritonitis; Aspergillusfumigatus; Drug resistance; Liposome amphotericin B; Voriconazole.

Publication types

Case Reports