Dual-ligand lanthanide metal-organic framework based ratiometric fluorescent platform for visual monitoring of aminoglycoside residues in food samples

Tingting Deng; Haibo He; Huinan Chen; Xitian Peng; Hongbo Li; Xiaoxia Yan; Yunyi Lei; Liqiang Luo

doi:10.1016/j.talanta.2024.126200

Dual-ligand lanthanide metal-organic framework based ratiometric fluorescent platform for visual monitoring of aminoglycoside residues in food samples

Talanta. 2024 May 8:276:126200. doi: 10.1016/j.talanta.2024.126200. Online ahead of print.

Authors

Tingting Deng¹, Haibo He², Huinan Chen³, Xitian Peng⁴, Hongbo Li⁵, Xiaoxia Yan¹, Yunyi Lei¹, Liqiang Luo¹

Affiliations

¹ Department of Chemistry, College of Sciences, Shanghai University, Shanghai, 200444, PR China.
² Department of Chemistry, College of Sciences, Shanghai University, Shanghai, 200444, PR China. Electronic address: hbhe2006@shu.edu.cn.
³ Department of Physics, College of Sciences, Shanghai University, Shanghai, 200444, PR China.
⁴ Institute of Agricultural Quality Standards and Testing Technology Research, Hubei Academy of Agricultural Sciences, Wuhan, 430064, PR China.
⁵ School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng, 224051, PR China.

PMID: 38735243
DOI: 10.1016/j.talanta.2024.126200

Abstract

Herein, a dual-emission Eu metal-organic framework (Eu-MOF) is prepared and used as the ratiometric fluorescence probe for ultrasensitive detection of aminoglycoside antibiotics (AGs). Due to the strong hydrogen bond interactions between AGs and Eu-MOF, the blue emission is enhanced while the red emission has little fluctuation in Eu-MOF with the addition of AGs, thus a good linear relationship with the logarithm of AGs concentrations from 0.001 to 100 μg/mL can be established for quantitative analysis. Good sensitivity with the detection limit of 0.33 ng/mL for apramycin, 0.32 ng/mL for amikacin and 0.30 ng/mL for kanamycin is achieved. The proposed assay demonstrates good selectivity and applicability for determination of AGs in real milk and honey samples. The Eu-MOF materials are further fabricated as fluorescent test papers for facile visual detection. The as-established ratio fluorescence platform offers a portable and economical way for rapid monitoring AGs residues in complex food samples.

Keywords: Aminoglycoside antibiotics; Dual emission Eu-MOF; Ratiometric fluorescence; Visual sensor.