Photoredox-Catalyzed Decarboxylative Cross-Coupling Reaction to Synthesis Unsymmetrical Diarylmethanes

Molecules. 2024 May 6;29(9):2156. doi: 10.3390/molecules29092156.

Abstract

The photoredox-catalyzed decarboxylative cross-coupling reaction of aryl acetic acids and aryl nitriles has been achieved under an argon atmosphere in high yields. This method provides a fast way to obtain prevalent aryl acetic acids from an abundant natural source. A tentative radical mechanism has been proposed.

Keywords: cross coupling; decarboxylative; photoredox catalyzed; unsymmetrical diarylmethanes.