An efficient Fusion-Purification Network for Cervical pap-smear image classification

Comput Methods Programs Biomed. 2024 Apr 30:251:108199. doi: 10.1016/j.cmpb.2024.108199. Online ahead of print.

Abstract

Background and objectives: In cervical cell diagnostics, autonomous screening technology constitutes the foundation of automated diagnostic systems. Currently, numerous deep learning-based classification techniques have been successfully implemented in the analysis of cervical cell images, yielding favorable outcomes. Nevertheless, efficient discrimination of cervical cells continues to be challenging due to large intra-class and small inter-class variations. The key to dealing with this problem is to capture localized informative differences from cervical cell images and to represent discriminative features efficiently. Existing methods neglect the importance of global morphological information, resulting in inadequate feature representation capability.

Methods: To address this limitation, we propose a novel cervical cell classification model that focuses on purified fusion information. Specifically, we first integrate the detailed texture information and morphological structure features, named cervical pathology information fusion. Second, in order to enhance the discrimination of cervical cell features and address the data redundancy and bias inherent after fusion, we design a cervical purification bottleneck module. This model strikes a balance between leveraging purified features and facilitating high-efficiency discrimination. Furthermore, we intend to unveil a more intricate cervical cell dataset: Cervical Cytopathology Image Dataset (CCID).

Results: Extensive experiments on two real-world datasets show that our proposed model outperforms state-of-the-art cervical cell classification models.

Conclusions: The results show that our method can well help pathologists to accurately evaluate cervical smears.

Keywords: Cervical cell image classification; Fusion purification network; Two branch.