Effects of different nutrition interventions on sarcopenia criteria in older people: A study protocol for a systematic review of systematic reviews with meta-analysis

PLoS One. 2024 May 10;19(5):e0302843. doi: 10.1371/journal.pone.0302843. eCollection 2024.

Abstract

Background: Sarcopenia, a subject of extensive research, has led to numerous clinical trials and systematic reviews (SR). These reviews aid healthcare professionals by summarizing results and conducting meta-analyses, enhancing reliability. However, the abundance of reviews complicates decision-making on sarcopenia management. To address this, SR of SR have emerged, consolidating data from various sources into comprehensive documents.

Objective: To assess the isolated impact of dietary interventions on sarcopenia's diagnostic criteria for older individuals.

Methods: A study protocol for a SR of SR, following Cochrane and PRISMA recommendations. The search strategy includes the MeSH 'sarcopenia' and its subheadings; 'aged' and its subheadings; 'nutrition' and its subheadings; and filter 'systematic review', performed at main databases. Selected studies must include older adults, submitted to nutritional interventions compared to control groups. Quantitative analyses will use inverse variance statistic method (random effects); the effect measures mean difference. Heterogeneity measured with Q-Test.

Results: The results of this SR of SR may provide valuable information about the sarcopenia treatment, deepening the knowledge about.

Conclusion: This protocol is reproducible, requires low cost and personnel, and may allow a higher understanding on sarcopenia treatment and management on older people.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Humans
  • Meta-Analysis as Topic*
  • Nutritional Status
  • Sarcopenia* / diagnosis
  • Sarcopenia* / diet therapy
  • Sarcopenia* / therapy
  • Systematic Reviews as Topic*

Grants and funding

This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES) – Finance Code 001.