Copper(II)/polyimide linked covalent organic framework as a powerful catalyst for the solvent-free microwave irradiation-based synthesis of 2,4,5-trisubstituted imidazoles

Mahnaz Sedaghat; Farid Moeinpour; Fatemeh S Mohseni-Shahri

doi:10.1002/ansa.202300012

Copper(II)/polyimide linked covalent organic framework as a powerful catalyst for the solvent-free microwave irradiation-based synthesis of 2,4,5-trisubstituted imidazoles

Anal Sci Adv. 2023 Apr 17;4(9-10):302-311. doi: 10.1002/ansa.202300012. eCollection 2023 Oct.

Authors

Mahnaz Sedaghat¹, Farid Moeinpour¹, Fatemeh S Mohseni-Shahri¹

Affiliation

¹ Department of Chemistry Bandar Abbas Branch Islamic Azad University Bandar Abbas Iran.

Abstract

Copper(II)/polyimide-linked covalent organic frameworks under solvent-free and microwave-assisted conditions have been used in an efficient one-pot protocol for the preparation of 2,4,5-trisubstituted imidazoles via benzil, aromatic aldehydes and ammonium acetate. By applying solvent-free conditions and microwave irradiation, three-component condensation provides safe operations, low pollution, quick access to products, and an easy set-up. As a result of its reusability, the catalyst can also be reutilized for many runs without missing any activity.

Keywords: 2,4,5‐trisubstituted imidazoles; covalent organic framework; microwave; solvent‐free.