A head-mounted photoacoustic fiberscope for hemodynamic imaging in mobile mice

Light Sci Appl. 2024 May 7;13(1):107. doi: 10.1038/s41377-024-01454-w.

Abstract

A miniaturized photoacoustic fiberscope has been developed, featuring a lateral resolution of 9 microns and a lightweight design at 4.5 grams. Engineered to capture hemodynamic processes at single-blood-vessel resolution at a rate of 0.2 Hz, this device represents an advancement in head-mounted tools for exploring intricate brain activities in mobile animals.