Towards multi-omics synthetic data integration

Brief Bioinform. 2024 Mar 27;25(3):bbae213. doi: 10.1093/bib/bbae213.

Abstract

Across many scientific disciplines, the development of computational models and algorithms for generating artificial or synthetic data is gaining momentum. In biology, there is a great opportunity to explore this further as more and more big data at multi-omics level are generated recently. In this opinion, we discuss the latest trends in biological applications based on process-driven and data-driven aspects. Moving ahead, we believe these methodologies can help shape novel multi-omics-scale cellular inferences.

Keywords: data-driven; machine learning; multi-omics; process-driven; synthetic data.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Algorithms*
  • Big Data
  • Computational Biology* / methods
  • Genomics / methods
  • Humans
  • Multiomics
  • Proteomics / methods