Basement membrane dynamics in living animals: Insights and pitfalls

J Cell Biol. 2024 Jul 1;223(7):e202402113. doi: 10.1083/jcb.202402113. Epub 2024 May 6.

Abstract

Recent studies with fluorophore-tagged basement membrane (BM) components have led to remarkable discoveries about BMs but also inconsistent interpretations. Here, we review types of BM dynamics, discuss how we conduct and interpret fluorophore-tagged BM studies, and highlight experimental conditions that are important to consider.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Basement Membrane* / metabolism
  • Fluorescent Dyes / chemistry
  • Humans

Substances

  • Fluorescent Dyes