A Rare Case of Renal Vein Thrombosis Secondary to Oral Contraceptive Pills

Cureus. 2024 Apr 4;16(4):e57604. doi: 10.7759/cureus.57604. eCollection 2024 Apr.

Abstract

Renal vein thrombosis (RVT) is a common complication of nephrotic syndrome and renal malignancy. However, its association with oral contraceptive use has rarely been reported. We report a case of a 29-year-old female with a history of oral contraceptive use, presenting with acute flank pain. On further investigation, she was found to have unilateral RVT. Oral contraception was discontinued, and she was started on therapeutic anticoagulation, initially with low-molecular-weight heparin, and then switched to apixaban. Her symptoms improved, and she is currently doing well. This case signifies the importance of proper history-taking and how oral contraception should be considered a significant risk factor for venous thromboembolism.

Keywords: direct oral anticoagulant; flank pain; oral contraceptive pill (ocp); renal vein thrombosis; venous thromboembolism (vte).

Publication types

  • Case Reports