The Benjamin Button effect on stem cells: Reversing the clock on aging immunity

Sci Immunol. 2024 May 3;9(95):eadq0013. doi: 10.1126/sciimmunol.adq0013. Epub 2024 May 3.

Abstract

Antibody-based therapy depletes myeloid-biased hematopoietic stem cells (my-HSCs) to rejuvenate the immune system and improve immune responses in aged mice.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aging* / immunology
  • Animals
  • Hematopoietic Stem Cell Transplantation
  • Hematopoietic Stem Cells* / immunology
  • Humans
  • Mice