Patient-specific beta-tricalcium phosphate scaffold for customized alveolar ridge augmentation: a case report : Case Report: patient-specific β-TCP scaffold for alveolar ridge CBR

Int J Implant Dent. 2024 May 1;10(1):21. doi: 10.1186/s40729-024-00541-2.

Abstract

Background: Beta-tricalcium phosphate (β-TCP) is a biocompatible ceramic material widely used in the field of oral regeneration. Due to its excellent biological and mechanical properties, it is increasingly utilized for alveolar ridge augmentation or guided bone regeneration (GBR). With recent advances in computer-aided design and manufacturing (CAD/CAM), β-TCP can now be used in the form of digitally designed patient-specific scaffolds for customized bone regeneration (CBR) of advanced defects in a two-stage implant therapy concept. In this case report following the CARE case report guidelines, we present a novel application of a patient-specific β-TCP scaffold in pre-implant mandibular alveolar ridge augmentation.

Case presentation: A 63-year-old female patient with significant horizontal bone loss in the posterior mandible was treated with a custom β-TCP scaffold in the context of a two-stage backward-planned implant therapy. Cone-beam computed tomography nine months after augmentation showed successful integration of the scaffold into the surrounding bone, allowing implant placement. Follow-up until two years after initial surgery showed excellent oral and peri-implant health.

Conclusions: This case highlights the potential of patient-specific β-TCP scaffolds for alveolar ridge augmentation and their advantage over traditional techniques, including avoidance of xeno-, allo-, and autografts. The results provide encouraging evidence for their use in clinical practice. Patient-specific β-TCP scaffolds may be a promising alternative for clinicians seeking to provide their patients with safe, predictable, and effective alveolar ridge augmentation results in customized bone regeneration procedures.

Keywords: CBR; Case report; Customized bone regeneration; Guided bone regeneration; Two-stage implant therapy; beta-tricalcium phosphate; β-TCP.

Publication types

  • Case Reports

MeSH terms

  • Alveolar Bone Loss / surgery
  • Alveolar Ridge Augmentation* / methods
  • Bone Regeneration / drug effects
  • Calcium Phosphates* / therapeutic use
  • Computer-Aided Design
  • Cone-Beam Computed Tomography*
  • Dental Implantation, Endosseous / methods
  • Female
  • Humans
  • Mandible / surgery
  • Middle Aged
  • Tissue Scaffolds*

Substances

  • Calcium Phosphates
  • beta-tricalcium phosphate