Reveal more mechanisms of precondition mesenchymal stem cells inhibiting inflammation

Yi Li; Qian-Qian Chen; En-Qiang Linghu

doi:10.4252/wjsc.v16.i4.459

Reveal more mechanisms of precondition mesenchymal stem cells inhibiting inflammation

World J Stem Cells. 2024 Apr 26;16(4):459-461. doi: 10.4252/wjsc.v16.i4.459.

Authors

Yi Li¹, Qian-Qian Chen², En-Qiang Linghu³

Affiliations

¹ Department of Gastroenterology, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
² Department of Gastroenterology, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China. qian_qian_chen@163.com.
³ Department of Gastroenterology and Hepatology, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.

Abstract

Hypoxia can get more ability to inhibit inflammation. But how it impact on survival time of mesenchymal stem cells (MSCs) is confusing and how preconditioned MSCs inhibiting inflammation are partially known. Those issues decided the value of preconditioned MSCs by hypoxia.

Keywords: Hypoxia; Hypoxia-inducible factor 1α; Inflammation; Macrophage; Mesenchymal stem cell.