The novel HLA-DPA1*02:86 allele was identified by next-generation sequencing

HLA. 2024 May;103(5):e15504. doi: 10.1111/tan.15504.

Abstract

HLA-DPA1*02:86 differs from HLA-DPA1*02:01:01 by a single nucleotide substitution at position 680 C > A in exon 4.

Keywords: HLA‐DPA1*02:86; next‐generation sequencing; novel allele.

MeSH terms

  • Alleles*
  • Base Sequence
  • Exons*
  • HLA-DP alpha-Chains* / genetics
  • High-Throughput Nucleotide Sequencing* / methods
  • Histocompatibility Testing* / methods
  • Humans
  • Polymorphism, Single Nucleotide
  • Sequence Analysis, DNA / methods

Substances

  • HLA-DP alpha-Chains
  • HLA-DPA1 antigen