Clinical Efficacy of Percutaneous Balloon Compression Combined with Carbamazepine in the Treatment of Trigeminal Neuralgia: A Retrospective Study

Ann Ital Chir. 2024;95(2):200-205. doi: 10.62713/aic.3209.

Abstract

Objective: To investigate the effect of percutaneous balloon compression combined with carbamazepine on patients with Trigeminal Neuralgia (TN).

Methods: The clinical data of 126 patients with TN admitted to our hospital from January, 2021 to January, 2022 were retrospectively analyzed. All patients underwent percutaneous balloon compression in our hospital. The patients were divided into a control group and an observation group, according to whether they continued to take carbamazepine after surgery. The general demographic data of patients, such as gender, age, family income, education level, pain site, diseased nerve, course of disease, and duration of pain were collected. Propensity score matching was used to balance the baseline data of the two groups, and the quality of life, treatment effect, and complications of the two groups were compared after matching.

Results: After treatment, the total effective rate of the observation group (95.00%) was higher than that of the control group (70.00%) (p < 0.05). Before treatment, there were no significant differences in the scores for quality of life dimensions between the two groups (p > 0.05). After treatment, the scores for each quality of life dimension in the observation group were higher than those in the control group. After treatment, the incidence of complications in the observation group (7.50%) was lower than that in the control group (30.00%) (p < 0.05).

Conclusions: Percutaneous balloon compression combined with carbamazepine can effectively enhance the treatment of patients by improving their quality of life and reducing the occurrence of complications. These results can improve the clinical management of TN.

MeSH terms

  • Aged
  • Analgesics, Non-Narcotic* / therapeutic use
  • Carbamazepine* / therapeutic use
  • Combined Modality Therapy
  • Female
  • Humans
  • Male
  • Middle Aged
  • Quality of Life
  • Retrospective Studies
  • Treatment Outcome
  • Trigeminal Neuralgia* / drug therapy
  • Trigeminal Neuralgia* / therapy

Substances

  • Carbamazepine
  • Analgesics, Non-Narcotic