Improving therapeutic outcomes in heart failure with reduced nonvalvular ejection fraction: A clinical study of heart failure education intervention

Xueli Tian; Xiaozeng Li; Qingqing Zhang; Xiangling Qiao; Xin Li; Zijian Zhang

doi:10.1002/clc.24265

Improving therapeutic outcomes in heart failure with reduced nonvalvular ejection fraction: A clinical study of heart failure education intervention

Clin Cardiol. 2024 May;47(5):e24265. doi: 10.1002/clc.24265.

Authors

Xueli Tian¹, Xiaozeng Li², Qingqing Zhang³, Xiangling Qiao³, Xin Li³, Zijian Zhang⁴

Affiliations

¹ Department of Pediatrics, The Second Affiliated Hospital of Xingtai Medical College, Xingtai, China.
² Ward One, Department of Cardiology, Xingtai Central Hospital, Xingtai, Hebei, China.
³ CCU, Department of Cardiology, Xingtai Central Hospital, Xingtai, Hebei, China.
⁴ Department of Emergency, Xingtai Central Hospital, Xingtai, Hebei, China.

Abstract

Objective: The current study delves into the impact of heart failure education intervention on improving therapeutic outcomes for heart failure (HF) patients with reduced nonvalvular ejection fraction.

Methods: There involved a total of 60 HF patients with non-valvular ejection fraction reduction who met the inclusion requirements. Patients enrolled were randomly distributed into an observation group and a control group. The observation group received heart failure education intervention, while the control group received conventional intervention. The therapeutic effect, changes in physical indicators, cardiac function indicators, coagulation function, self-management scale scores, and the incidence of adverse cardiovascular events were meticulously evaluated.

Results: The total effective proportion in the observation group was 96.67%, which was significantly higher than the control group's proportion of 76.67% (p < .05). After treatment, several parameters in the observation group showed significant improvements compared to the control group: hs-CRP, IL-6, LVEDV value, LVESV value, PT value, APTT value, and TT value were all evidently lower in the observation group. Additionally, the cardiac index, LVEF value, and heart failure self-management scale fraction were significantly higher in the observation group compared to the control group (p < .05). Furthermore, the incidence of adverse cardiovascular events in the observation group was only 6.67%, which was significantly lower than the control group's incidence of 20.00% (p < .05).

Conclusion: Heart failure education intervention demonstrates effectiveness in improving the therapeutic outcomes for HF patients and reduced nonvalvular ejection fraction. Additionally, it enhances patients' self-management abilities. Given these positive results, it is highly recommended to promote and implement HF education intervention in clinical practice.

Keywords: heart failure; heart failure education; reduced nonvalvular ejection fraction; therapeutic effect.

Publication types

Randomized Controlled Trial

MeSH terms

Aged
Female
Heart Failure* / physiopathology
Heart Failure* / therapy
Humans
Male
Middle Aged
Patient Education as Topic* / methods
Stroke Volume* / physiology
Treatment Outcome
Ventricular Function, Left* / physiology