Application of three-dimensional speckle tracking technique in measuring left ventricular myocardial function in patients with diabetes

World J Diabetes. 2024 Apr 15;15(4):783-792. doi: 10.4239/wjd.v15.i4.783.

Abstract

Background: Diabetic cardiomyopathy is considered as a chronic complication of diabetes mellitus (DM). Therefore, early detection of left ventricular systolic function (LVSF) damage in DM is essential.

Aim: To explore the use of the three-dimensional speckle tracking technique (3D-STI) for measuring LVSF in DM patients via meta-analysis.

Methods: The electronic databases were retrieved from the initial accessible time to 29 April 2023. The current study involved 9 studies, including 970 subjects. We carried out this meta-analysis to estimate myocardial function in DM compared with controls according to myocardial strain attained by 3D-STI.

Results: Night articles including 970 subjects were included. No significant difference was detected in the left ventricular ejection fraction between the control and the diabetic group (P > 0.05), while differences in global longitudinal strain, global circumferential strain, global radial strain, and global area strain were markedly different between the controls and DM patients (all P < 0.05).

Conclusion: The 3D-STI could be applied to accurately measure early LVSF damage in patients with DM.

Keywords: Diabetes mellitus; Left ventricular systolic dysfunction; Meta analysis; Three-dimensional speckle tracking echocardiography.