Histamine Intolerance: Symptoms, Diagnosis, and Beyond

Nutrients. 2024 Apr 19;16(8):1219. doi: 10.3390/nu16081219.

Abstract

Histamine intolerance is a condition characterized by the accumulation of histamine to a point that exceeds the body's capacity to eliminate it. Researchers have attributed several reasons to this condition, such as genetic factors, alcohol, and dietary deficiencies, among other elements. Symptoms of histamine intolerance have been found to extend beyond the gastrointestinal tract and to the whole body, with these symptoms being sporadic and non-specific. This review will explore various aspects related to histamine intolerance, such as its causes, symptoms, diagnosis, and information related to management.

Keywords: diamine oxidase (DAO); food intolerance; histamine; histamine intolerance.

Publication types

  • Review

MeSH terms

  • Food Hypersensitivity / diagnosis
  • Food Intolerance* / diagnosis
  • Histamine* / metabolism
  • Humans

Substances

  • Histamine

Grants and funding

This research received no external funding.