Identification of a novel ALK inhibitor-sensitive PRKCE-ALK gene fusion in lung adenocarcinoma

Lung Cancer. 2024 May:191:107797. doi: 10.1016/j.lungcan.2024.107797. Epub 2024 Apr 21.
No abstract available

Publication types

  • Letter
  • Case Reports

MeSH terms

  • Adenocarcinoma of Lung* / drug therapy
  • Adenocarcinoma of Lung* / genetics
  • Adenocarcinoma of Lung* / pathology
  • Adenocarcinoma* / drug therapy
  • Adenocarcinoma* / genetics
  • Adenocarcinoma* / pathology
  • Anaplastic Lymphoma Kinase* / antagonists & inhibitors
  • Anaplastic Lymphoma Kinase* / genetics
  • Crizotinib / pharmacology
  • Crizotinib / therapeutic use
  • Female
  • Humans
  • Lung Neoplasms* / drug therapy
  • Lung Neoplasms* / genetics
  • Lung Neoplasms* / pathology
  • Male
  • Middle Aged
  • Oncogene Proteins, Fusion* / genetics
  • Protein Kinase Inhibitors* / pharmacology
  • Protein Kinase Inhibitors* / therapeutic use
  • Receptor Protein-Tyrosine Kinases / genetics

Substances

  • Anaplastic Lymphoma Kinase
  • ALK protein, human
  • Protein Kinase Inhibitors
  • Oncogene Proteins, Fusion
  • Receptor Protein-Tyrosine Kinases
  • Crizotinib