Myxofibrosarcoma of the Chest Wall Detected on 99mTc-MDP Whole-Body Bone Scan

Diagnostics (Basel). 2024 Apr 22;14(8):857. doi: 10.3390/diagnostics14080857.

Abstract

Myxofibrosarcoma is a type of soft tissue sarcoma, predominantly characterized by a high propensity for local recurrence, albeit demonstrating a relatively diminished risk for distant metastasis. Its prevalence is notably higher in elderly patients. Here, we present a case of a 73-year-old woman diagnosed with Myxofibrosarcoma. She was subjected to a whole-body bone scan using 99mTc-methylene diphosphonate (MDP) to survey potential bony metastasis. It revealed marked MDP accumulation with peripheral soft tissue uptake in the right lateral chest region of this patient. This imaging phenotype could potentially be attributed to the augmented vascularity within the tumor, a finding that was prominently displayed in this particular case.

Keywords: bone scan; intercostal muscle invasion; lung metastasis; myxofibrosarcoma.

Grants and funding

This research received no external funding.