Acquired tracheomalacia due to SARS-CoV-2 pneumonia

Clin Respir J. 2024 Jan;18(1):e13719. doi: 10.1111/crj.13719. Epub 2023 Dec 20.

Abstract

Introduction: Several studies mentioned parenchymal findings after SARS-CoV-2 pneumonia, but few studies have mentioned alterations in the airways. The aim of this study was to estimate the prevalence of tracheomalacia and to analyse the clinical characteristics in a cohort of patients with SARS-CoV-2.

Methods: The study population consisted of all patients with SARS-CoV-2 admitted a hospital serving a population of 500 000 inhabitants. Patients were visited between 2 and 6 months after hospital discharge. In this visit, all patients were subjected to an exhaustive clinical questionnaire and underwent clinical examination, pulmonary function tests and chest CT.

Results: From February 2020 to August 2021, 1920 patients were included in the cohort and tracheomalacia was observed in 15 (0.8%) on expiratory HRCT imaging. All patients with tracheomalacia also presented ground glass opacities in the CT scan and 12 patients had airway sequelae.

Conclusions: Tracheomalacia is an exceptional sequela of SARS-CoV-2 survivors.

Keywords: COVID‐19; infection; inflammation.

Publication types

  • Letter

MeSH terms

  • Adult
  • Aged
  • COVID-19* / complications
  • COVID-19* / diagnosis
  • COVID-19* / epidemiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Respiratory Function Tests
  • SARS-CoV-2*
  • Tomography, X-Ray Computed* / methods
  • Tracheomalacia* / diagnostic imaging
  • Tracheomalacia* / epidemiology