Sleep Disorders in Patients with Severe COVID-19 Treated in the Intensive Care Unit: A Real-Life Descriptive Study in Vietnam

Discov Med. 2024 Apr;36(183):690-698. doi: 10.24976/Discov.Med.202436183.65.

Abstract

Background: Coronavirus disease 2019 (COVID-19) patients with sleep disorders may be at greater risk for respiratory exacerbation or death compared to those without. After being infected with COVID-19, patients have many symptoms related to sleep disorders, especially those with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection. This study aimed to evaluate sleep disturbances in patients with severe SARS-CoV-2 infection who were treated in the Intensive Care Unit (ICU).

Methods: This cross-sectional study used the questionnaire provided by the Vietnam Sleep Disorder Study (ViSDiS) research, elaborated by the Vietnam Society of Sleep Medicine (VSSM). Seventy-seven COVID-19 patients were included.

Results: There was a significant difference in sleep status before and after SARS-CoV-2 infection among participants. Up to 83% of them reported experiencing insomnia after illness, 60% reported having frequent nightmares, and more than half of participants reported nocturia (p < 0.0001). More than 81.8% of patients with severe SARS-CoV-2 infection were unsatisfied with their sleep quality during hospitalization After SARS-CoV-2 infection, only 2.6% of participants felt they had good quality sleep (p < 0.0001). The majority of patients suffered from fatigue after SARS-CoV-2 infection, including a lack of energy, feeling heaviness in their limbs, aggravation of pre-existing sleep disorders, idleness, constant fatigue throughout the day, and difficulty concentrating.

Conclusion: Sleep problems are highly prevalence among hospitalized patients with severe COVID-19 in the ICU. Healthcare providers should pay attention to sleep problems and their associated symptoms to initiate appropriate treatment to improve severe COVID-19 patients' health status and minimize the risk of death.

Keywords: COVID-19; ICU; hospitalized patients; insomnia; sleep disorders.

MeSH terms

  • Adult
  • Aged
  • COVID-19* / complications
  • COVID-19* / epidemiology
  • COVID-19* / therapy
  • Cross-Sectional Studies
  • Female
  • Humans
  • Intensive Care Units* / statistics & numerical data
  • Male
  • Middle Aged
  • SARS-CoV-2*
  • Severity of Illness Index
  • Sleep Quality
  • Sleep Wake Disorders* / epidemiology
  • Surveys and Questionnaires
  • Vietnam / epidemiology