Sunlight: Time for a Rethink?

J Invest Dermatol. 2024 Apr 24:S0022-202X(24)00280-X. doi: 10.1016/j.jid.2023.12.027. Online ahead of print.

Abstract

UVR is a skin carcinogen, yet no studies link sun exposure to increased all-cause mortality. Epidemiological studies from the United Kingdom and Sweden link sun exposure with reduced all-cause, cardiovascular, and cancer mortality. Vitamin D synthesis is dependent on UVB exposure. Individuals with higher serum levels of vitamin D are healthier in many ways, yet multiple trials of oral vitamin D supplementation show little benefit. Growing evidence shows that sunlight has health benefits through vitamin D-independent pathways, such as photomobilization of nitric oxide from cutaneous stores with reduction in cardiovascular morbidity. Sunlight has important systemic health benefit as well as risks.

Keywords: Environment and public health; Health status; Mortality; Nitric oxide; UVR.

Publication types

  • Review