Combined emapalumab and ruxolitinib in patients with haemophagocytic Lymphohistiocytosis

Yue Song; Fei Zhou; Feng Du; Ziyan Wang; Liyun Bai; Yifang Yao; Limin Liu; Xiao Ma; Suning Chen; Depei Wu; Xuefeng He

doi:10.1038/s41408-024-01056-0

Combined emapalumab and ruxolitinib in patients with haemophagocytic Lymphohistiocytosis

Blood Cancer J. 2024 Apr 24;14(1):70. doi: 10.1038/s41408-024-01056-0.

Authors

Yue Song^#^{1

2}, Fei Zhou^#^{1

2}, Feng Du³, Ziyan Wang³, Liyun Bai³, Yifang Yao³, Limin Liu^{1

2}, Xiao Ma^{1

2}, Suning Chen^{1

2}, Depei Wu^{4

5}, Xuefeng He^{6

7}

Affiliations

¹ National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.
² Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, 215031, China.
³ Department of hematology, Soochow Hopes Hematonosis Hospital, Suzhou, 215128, Jiangsu, China.
⁴ National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China. wudepei@suda.edu.cn.
⁵ Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, 215031, China. wudepei@suda.edu.cn.
⁶ National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China. hexuefeng@suda.edu.cn.
⁷ Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, 215031, China. hexuefeng@suda.edu.cn.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Aged
Antibodies, Monoclonal / therapeutic use
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Female
Humans
Lymphohistiocytosis, Hemophagocytic* / drug therapy
Male
Middle Aged
Nitriles* / therapeutic use
Pyrazoles* / therapeutic use
Pyrimidines* / therapeutic use
Young Adult

Substances

ruxolitinib
Nitriles
Pyrazoles
Pyrimidines
Antibodies, Monoclonal

Grants and funding

2023M732540/China Postdoctoral Science Foundation