Mendelian randomization analysis reveals no causal relationship between appendectomy and inflammatory bowel disease

J Gastrointest Surg. 2024 Apr 22:S1091-255X(24)00420-7. doi: 10.1016/j.gassur.2024.04.019. Online ahead of print.

¹ Department of General Surgery (Hepatopancreatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, People's Republic of China; Academician (Expert) Workstation of Sichuan Province, Metabolic Hepatobiliary and Pancreatic Diseases Key Laboratory of Luzhou City, The Affiliated Hospital of Southwest Medical University, Luzhou, People's Republic of China.
² Department of General Surgery (Hepatopancreatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, People's Republic of China; Academician (Expert) Workstation of Sichuan Province, Metabolic Hepatobiliary and Pancreatic Diseases Key Laboratory of Luzhou City, The Affiliated Hospital of Southwest Medical University, Luzhou, People's Republic of China. Electronic address: 344920646@qq.com.
³ Department of General Surgery (Hepatopancreatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, People's Republic of China; Academician (Expert) Workstation of Sichuan Province, Metabolic Hepatobiliary and Pancreatic Diseases Key Laboratory of Luzhou City, The Affiliated Hospital of Southwest Medical University, Luzhou, People's Republic of China. Electronic address: liboer2002@126.com.

No abstract available

Keywords: Appendectomy; Causality; Genome-wide association studies; Inflammatory bowel disease; Mendelian randomization.