A new xanthone isolated from Garcinia bracteata and its important effect on NO levels

Nat Prod Res. 2024 Apr 24:1-7. doi: 10.1080/14786419.2024.2344742. Online ahead of print.

Abstract

A new xanthone, allanxanthone F (1), and 10 known compounds were isolated from the ethanol extract of Garcinia bracteata. The structure of compound 1 was elucidated based on spectroscopic methods (UV, IR, HR-ESI-MS, and NMR). In addition, compounds 1-9 were assessed for their anti-inflammatory activities based on the expression of nitric oxide (NO) levels on lipopolysaccharide (LPS)-induced RAW264.7 macrophages, and compounds 1-3, 4 and 6-9 suggested potential anti-inflammatory activities.

Keywords: Clusiaceae; Garcinia bracteata; anti-inflammatory; xanthones.