Revisiting dexamethasone use in the pediatric emergency department

Curr Opin Pediatr. 2024 Jun 1;36(3):251-255. doi: 10.1097/MOP.0000000000001351. Epub 2024 Apr 1.

Abstract

Purpose of review: Dexamethasone is an essential treatment for common pediatric inflammatory, airway, and respiratory conditions. We aim to provide up-to-date recommendations for treatment of anaphylaxis, croup, coronavirus disease, multisystem inflammatory syndrome in children, and asthma with dexamethasone for use in the pediatric emergency department.

Recent findings: Literature largely continues to support the use of dexamethasone in most of the above conditions, however, recommendations for dosing and duration are evolving.

Summary: The findings discussed in this review will enable pediatric emergency medicine providers to use dexamethasone effectively as treatment of common pediatric conditions and minimize the occurrence of side-effects caused by gratuitous corticosteroid use.

Publication types

  • Review

MeSH terms

  • Anaphylaxis* / drug therapy
  • Asthma* / drug therapy
  • COVID-19 / complications*
  • Child
  • Croup* / drug therapy
  • Dexamethasone* / administration & dosage
  • Dexamethasone* / therapeutic use
  • Emergency Service, Hospital*
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / therapeutic use
  • Humans
  • Pediatric Emergency Medicine / methods
  • Systemic Inflammatory Response Syndrome* / drug therapy

Substances

  • Dexamethasone
  • Glucocorticoids

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related