Malignancy and "Violated Neck" Rates in Consecutive Cohort of 79 Adult Patients With Solitary Cystic Neck Mass-Lessons Learned and Recommendations for Clinical Practice Guidelines

Jure Pupić-Bakrač; Sandeep Jayasekara; Prasangi M Peiris; Liyanaarachchige A H Jayasinghe; Kanchana Kapugama; Nadeena S S Jayasuriya; Parakrama Wijekoon; Manjula Attygalla

doi:10.1097/SCS.0000000000010122

Malignancy and "Violated Neck" Rates in Consecutive Cohort of 79 Adult Patients With Solitary Cystic Neck Mass-Lessons Learned and Recommendations for Clinical Practice Guidelines

J Craniofac Surg. 2024 Apr 23. doi: 10.1097/SCS.0000000000010122. Online ahead of print.

Authors

Jure Pupić-Bakrač¹, Sandeep Jayasekara², Prasangi M Peiris², Liyanaarachchige A H Jayasinghe², Kanchana Kapugama², Nadeena S S Jayasuriya², Parakrama Wijekoon², Manjula Attygalla²

Affiliations

¹ Department of Otorhinolaryngology and Maxillofacial Surgery, General Hospital Zadar, Zadar, Croatia.
² Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, University of Peradeniya, Peradeniya, Sri Lanka.

PMID: 38651860
DOI: 10.1097/SCS.0000000000010122

Abstract

Objective: The neck region is a common site for solitary cystic neck mass (SCNM) of various etiologies, including congenital, inflammatory, and neoplastic. In adults, the primary focus is excluding malignancy. The objective of this study was to retrospectively analyze the accuracy of available diagnostic technologies for the differentiation of benign and malignant SCNM in adult patients. The study aimed to develop new clinical practice guidelines for evaluating and managing SCNM.

Methods: The primary predictive variables were the diagnostic utilities of fine-needle aspiration cytology (FNAC), ultrasound (U/S), multislice computed tomography, and magnetic resonance imaging. The study's endpoint was the overall diagnostic accuracy in differentiating between benign and malignant SCNM. The final diagnosis was based on histopathology.

Results: The study included 79 adult patients: 55 (69.62%) male and 24 (30.38%) female (P<0.05). The mean age at presentation was 42.1 years (range: 18-84 years). Solitary cystic neck mass was distributed in the anterior neck region in 30 (37.97%) patients and the posterolateral neck regions in 49 (62.03%) patients (P<0.05). The posterolateral neck regions had a significantly higher rate of malignant SCNM than the anterior neck region [19/49 (38.78%) versus 1/30 (3.33%)] (P<0.05). There was no statistically significant difference between the U/S+FNAC and U/S+FNAC+multislice computed tomography and/or magnetic resonance imaging groups in differentiating benign and malignant SCNM (40/42 versus 36/37, P>0.05). "Violated neck" was recorded in 2 cases.

Conclusion: A systematic investigation protocol should be applied to evaluate adult patients with SCNM.