Beyond Rarity: Insights Into the Diagnosis and Histopathology of Breast Granular Cell Tumors

Cureus. 2024 Mar 23;16(3):e56774. doi: 10.7759/cureus.56774. eCollection 2024 Mar.

Abstract

Breast granular cell tumors, which are benign and rare tumors of the breast, pose a diagnostic challenge due to their rarity and nuanced clinical presentations. This article explores a unique case of a 41-year-old female with a biopsy-confirmed granular cell tumor, shedding light on the intricacies involved in diagnosis. Rooted in a neuroectodermal origin, particularly Schwann cells, these tumors demand a multidimensional diagnostic approach for accurate identification. Despite their predominantly benign nature, malignant variants exist, necessitating a thorough histomorphology examination, supported by immunohistochemistry, for precise classification. This article contributes to our understanding of breast pathology and emphasizes the pivotal role of histopathology in unraveling complexities associated with granular cell tumors, reaffirming the importance of a comprehensive diagnostic approach.

Keywords: breast cancer; breast cancer biology; breast ihc; breast pathology; granular cell tumor; pathology.

Publication types

  • Case Reports