Integrated single-cell RNA sequencing and spatial transcriptomics analysis reveals the tumour microenvironment in patients with endometrial cancer responding to anti-PD-1 treatment

Clin Transl Med. 2024 Apr;14(4):e1668. doi: 10.1002/ctm2.1668.

Authors

Junfeng Chen^#¹, Yunfeng Song^#², Jian Huang¹, Xiaoping Wan^{1

2}, Yiran Li^{1

2}

Affiliations

¹ Department of Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
² Department of Gynecology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Endometrial Neoplasms* / drug therapy
Endometrial Neoplasms* / genetics
Endometrial Neoplasms* / pathology
Female
Gene Expression Profiling / methods
Humans
Sequence Analysis, RNA / methods
Single-Cell Analysis* / methods
Transcriptome / genetics
Tumor Microenvironment* / drug effects
Tumor Microenvironment* / genetics

Grants and funding