Atypical Gradenigo's syndrome in a pediatric case: A critical review of neuroimaging

Radiol Case Rep. 2024 Apr 13;19(7):2633-2638. doi: 10.1016/j.radcr.2024.03.037. eCollection 2024 Jul.

Abstract

Gradenigo's syndrome, a rare but serious complication of otitis media, encompasses a triad of symptoms including otalgia, facial palsy, and abducens nerve palsy, pointing to the involvement of the petrous apex. This case report presents an 11-year-old boy with an atypical manifestation of Gradenigo's syndrome, characterized by the absence of classic features such as abducens nerve palsy and purulent otorrhea. MRI findings were significant for petrous apicitis extending to Meckel's cave and the cavernous sinus, along with abscess formation and clivus osteomyelitis. The report highlights the critical role of advanced neuroimaging, particularly MRI, in the diagnosis and management of this condition. It underscores the importance of recognizing atypical presentations of Gradenigo's syndrome and the effectiveness of imaging-guided conservative treatment strategies in pediatric otological cases.

Keywords: Gradenigo's syndrome; Meckel's cave; Osteomyelitis; Pediatrics; Petrositis; Petrous apicitis.

Publication types

  • Case Reports