Hereditary kidney disease is an important cause of chronic kidney disease in children. With the progress of genome sequencing, single-cell technology, and organoid cultures, the research on hereditary kidney disease has entered a new era. How to integrate big data resources, discover new disease-causing genes, and develop effective treatment methods will be the focus of future research. This article discusses the classification, research progress, challenges and prospects of pediatric hereditary kidney disease, so as to provide valuable insights into the research of hereditary kidney disease in children.
遗传性肾脏病是儿童慢性肾脏病的重要病因。随着基因组测序、单细胞技术、类器官培养等研究进展，遗传性肾脏病的研究已进入新时代。如何整合大数据资源，发现新的致病基因，开发有效的治疗方法，是未来的研究重点。本文从儿童遗传性肾脏病的分类、研究进展、面临的困难等方面做总结和展望，以期为儿童遗传性肾脏病的研究提供参考和借鉴。.