Prevalence of major depressive disorder and post-traumatic stress disorder among first-time sleep center attendees

Julie Garrivet; Bénédicte Gohier; Gabriel Laviole; Nicole Meslier; Frédéric Gagnadoux; Wojciech Trzepizur

doi:10.1016/j.sleep.2024.04.013

Prevalence of major depressive disorder and post-traumatic stress disorder among first-time sleep center attendees

Sleep Med. 2024 Apr 15:119:53-57. doi: 10.1016/j.sleep.2024.04.013. Online ahead of print.

Authors

Julie Garrivet¹, Bénédicte Gohier², Gabriel Laviole³, Nicole Meslier³, Frédéric Gagnadoux⁴, Wojciech Trzepizur⁴

Affiliations

¹ Department of Psychiatry and Addictiction, CHU Angers, 49100 Angers, France; Department of Respiratory and Sleep Medicine, Angers University hospital, Angers, France. Electronic address: julie.garrivet@chu-angers.fr.
² Department of Psychiatry and Addictiction, CHU Angers, 49100 Angers, France; Université d'Angers, Université de Nantes, LPPL, SFR CONFLUENCES, F-49000 Angers, France.
³ Department of Respiratory and Sleep Medicine, Angers University hospital, Angers, France.
⁴ Department of Respiratory and Sleep Medicine, Angers University hospital, Angers, France; INSERM, CNRS, MITOVASC, University of Angers, Angers, France.

PMID: 38643516
DOI: 10.1016/j.sleep.2024.04.013

Abstract

Background: Sleep disorders and psychiatric disorders stand in a bidirectional relationship. Sleep complaints are prominent in populations with psychiatric disorders, especially amongst people with major depressive disorder (MDD) and post-traumatic stress disorder (PTSD). Consultations at sleep clinics offer opportunities to screen psychiatric disorders and to propose primary psychiatric care.

Methods: This descriptive study was conducted on 755 patients making their first visit to sleep clinic, with 574 seeking consultation for suspected obstructive sleep apnoea-hypopnoea syndrome (OSAHS), 139 for complaints of insomnia, and 42 for complaints of hypersomnia. The results of 387 screening scales for MDD (BDI-II) and 403 for TSPT (PCL-5) were compared according to the reason given for the consultation.

Results: In the whole group, 12.1 % of patients presented a positive MDD screening and 4.9 % for PTSD. Among patients presenting with insomnia, 19.8 % had a positive screening for MDD, as compared to 9.3 % in patients presenting with suspected OSAHS (p = 0.02). Regarding PTSD, 9.7 % of patients seeking consultation because of insomnia had a positive screening, compared to 2.9 % among patients with suspected OSAHS (p = 0.03). Among patients with a positive screening for MDD, 40.5 % were not receiving antidepressant or mood stabilizer treatment.

Conclusion: Positive screening for MDD and PTSD are frequent in patients who attend sleep centers, especially amongst those presenting with insomnia. Nearly half of the patients with positive screening for MDD or PTSD were not receiving a dedicated pharmacological treatment. These figures emphasize systematic screening for psychiatric disorders in sleep clinics.

Keywords: Chronic insomnia; Hypersomnia; Major depressive disorder; Obstructive sleep apnoea-hypopnea syndrome; Post-traumatic stress disorder; Sleep medicine.