Breast mucosa-associated lymphoid tissue lymphoma: A case report and literature review

Medicine (Baltimore). 2024 Apr 19;103(16):e37895. doi: 10.1097/MD.0000000000037895.

Abstract

Background: Mucosa-associated lymphoid tissue (MALT) lymphoma, also known as extranodal marginal zone lymphoma, is more commonly detected in the stomach and rarely in the breast. Our study presented a clinical and pathological examination of a patient diagnosed with breast MALT lymphoma, supplemented with pertinent research, to offer guidance for the diagnosis and treatment of this condition.

People concerns: The occurrence of breast MALT lymphoma has risen in the past decade, but its etiology, progression and treatment response are less well-studied.

Diagnosis: Breast MALT lymphoma was diagnosed by excisional biopsy and histopathology.

Interventions: Following breast MALT lymphoma diagnosis, the patient was transferred to the hematology department for further treatment, and she made the decision to continue observing.

Outcomes: After 3 months of observation, the patient remained asymptomatic.

Conclusion: Breast MALT lymphoma is an indolent disease with an asymptomatic presentation, There are no standardized treatment guidelines for breast MALT lymphoma, treatment must be tailored to the patient willingness to treat and the severity of the disease. Hence, in order to give patients a better chance of cure, more research is needed to explore its pathogenesis and more clinical trials are needed investigate the treatment of this disease.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Biopsy
  • Breast Neoplasms* / diagnosis
  • Breast Neoplasms* / pathology
  • Breast Neoplasms* / therapy
  • Female
  • Humans
  • Lymphoma, B-Cell, Marginal Zone* / drug therapy
  • Lymphoma, B-Cell, Marginal Zone* / therapy