Association between Causative Pathogen and Occurrence of Infection-Related Glomerulonephritis in Infective Endocarditis

Nabin K Shrestha; Emese C Kanyo; Georges N Nakhoul; Leal C Herlitz; Steven M Gordon

doi:10.1093/cid/ciae213

Association between Causative Pathogen and Occurrence of Infection-Related Glomerulonephritis in Infective Endocarditis

Clin Infect Dis. 2024 Apr 18:ciae213. doi: 10.1093/cid/ciae213. Online ahead of print.

Authors

Nabin K Shrestha¹, Emese C Kanyo², Georges N Nakhoul³, Leal C Herlitz⁴, Steven M Gordon¹

Affiliations

¹ From the Department of Infectious Diseases, Cleveland Clinic, Cleveland, Ohio.
² Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, Cleveland, Ohio.
³ From the Department of Kidney Medicine, Cleveland Clinic, Cleveland, Ohio.
⁴ From the Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio.

PMID: 38640140
DOI: 10.1093/cid/ciae213

Abstract

Among patients with pathologically-proven infective endocarditis, the association of pathogen with occurrence of infection-related glomerulonephritis (IRGN) was examined in 48 cases of IRGN and 192 propensity score-matched controls. Bartonella was very strongly associated with IRGN (OR 38.2, 95% C.I. 6.7-718.8, p-value <.001); other microorganisms were not.

Keywords: Bartonella; bacterial; case-control studies; endocarditis; glomerulonephritis.

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