Mini-tablets current use and future opportunities - An APV course on manufacturing, packaging, characterization and use of minitablets

Susanne Page; Timo Rode; Jörg Breitkreutz; Leonie Wagner-Hattler

doi:10.1016/j.ejpb.2024.114294

Mini-tablets current use and future opportunities - An APV course on manufacturing, packaging, characterization and use of minitablets

Eur J Pharm Biopharm. 2024 Apr 16:114294. doi: 10.1016/j.ejpb.2024.114294. Online ahead of print.

Authors

Susanne Page¹, Timo Rode², Jörg Breitkreutz³, Leonie Wagner-Hattler⁴

Affiliations

¹ Pharmaceutical R&D, F. Hoffmann-La Roche Ltd., Grenzacherstr. 124, CH-4070 Basel, Switzerland. Electronic address: susanne.page@roche.com.
² Pharmaceutical Development, Nordmark Pharma GmbH, Pinnauallee 4, 25436 Uetersen, Germany. Electronic address: timo.rode@nordmark-pharma.de.
³ Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine-Universität Düsseldorf, Universitätsstraße 1, Geb. 26.22, 40225 Düsseldorf, Germany. Electronic address: joerg.breitkreutz@uni-duesseldorf.de.
⁴ Pharmaceutical R&D, F. Hoffmann-La Roche Ltd., Grenzacherstr. 124, CH-4070 Basel, Switzerland. Electronic address: leonie.wagner@roche.com.

PMID: 38636884
DOI: 10.1016/j.ejpb.2024.114294

Abstract

Recently, APV organized in collaboration with Fette Compacting GmbH a course on current use and future opportunities of mini-tablets. The course including a workshop was attended by 30 participants and focused on the manufacturing, packaging, characterization and medical use of mini-tablets. It took place at the Headquarter of Fette Compacting GmbH in Schwarzenbek. This article provides an overview on the topics presented and discussed during the course.

Keywords: Acceptability; Analytics; Controlled release; Individualized dosing; Manufacturing; Mini-tablets; Packaging; Regulatory; Swallowability; Taste masking.