Recent developments in ureteral stent: Substrate material, coating polymer and technology, therapeutic function

Colloids Surf B Biointerfaces. 2024 Jun:238:113916. doi: 10.1016/j.colsurfb.2024.113916. Epub 2024 Apr 12.

Abstract

The ureteral stent is an effective treatment for clinical ureteral stricture following urological surgery, and the functional coating of the stent could effectively inhibit bacterial colonization and other complications. The present review provides an analysis and description of the materials used in ureteral stents and their coatings. Emphasis is placed on the technological advancements of functional coatings, taking into consideration the characteristics of these materials and the properties of their active substances. Furthermore, recent advances in enhancing the therapeutic efficacy of functional coatings are also reviewed. It is anticipated that this article will serve as a valuable reference providing insights for future research development on new drug-loaded ureteral stents.

Keywords: Coating materials; Coating preparation; Functional application; Ureteral stent.

Publication types

  • Review

MeSH terms

  • Animals
  • Coated Materials, Biocompatible* / chemistry
  • Coated Materials, Biocompatible* / pharmacology
  • Humans
  • Polymers* / chemistry
  • Stents*
  • Ureter* / surgery

Substances

  • Polymers
  • Coated Materials, Biocompatible