Efficacy of Biosilicate Glass-ceramic and Fluoride Varnish in the Treatment of Dentin Hypersensitivity-A Randomized Controlled Clinical Trial

V M Roriz; Mll Santana; V L Boaventura; E D Zanotto; O Peitl Filho; D R Dias

doi:10.2341/23-077-C

Efficacy of Biosilicate Glass-ceramic and Fluoride Varnish in the Treatment of Dentin Hypersensitivity-A Randomized Controlled Clinical Trial

Oper Dent. 2024 Apr 17. doi: 10.2341/23-077-C. Online ahead of print.

Authors

V M Roriz¹, Mll Santana², V L Boaventura³, E D Zanotto⁴, O Peitl Filho⁵, D R Dias⁶

Affiliations

¹ Virgílio Moreira Roriz, adjunct professor, Periodontology, Dentistry School, Federal University of Goias, Goiania, Goias, Brazil.
² Maria Luiza Lima Santana, MDSc, Federal University of Goias, Goiania, Goias, Brazil.
³ Verônica Lima Boaventura, private clinical practice, Anápolis, Goias, Brazil.
⁴ Edgar Dutra Zanotto, full professor, Department of Materials Engineering, Federal University of São Carlos, São Carlos, São Paulo, Brazil.
⁵ Oscar Peitl Filho, full professor, Department of Materials Engineering, Federal University of São Carlos, São Carlos, São Paulo, Brazil.
⁶ *Danilo Rocha Dias, adjunct professor, Department of Restorative Dentistry, Dentistry School, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais- Brazil.

PMID: 38632860
DOI: 10.2341/23-077-C

Abstract

Objective: The objective of this study was to compare the efficacy of Biosilicate and Duraphat in the treatment of dentin hypersensitivity (DH).

Methods and materials: This clinical trial was conducted with young adults presenting DH. A visual analogue scale (VAS) was used to assess the level of pain, using volatile and tactile tests. Forty participants presenting two teeth with DH were included, and these teeth were divided into two groups according to the treatment: Biosilicate or Duraphat. Each product was randomly applied on one tooth per participant once a week for 4 weeks and evaluated every 15 days for 60 days after the last application.

Results: The mean and standard deviation (SD) of VAS values for the initial volatile sensitivity evaluation were 6.18 (1.99) and 6.08 (1.98) for the Biosilicate and Duraphat groups, respectively, and at the fourth week 0.48 (1.5) and 0.83 (1.58). After 60 days, the volatile sensitivity showed the following values: 0.63 (1.19) for Biosilicate and 1.03 (1.07) for Duraphat. The intragroup comparison showed a significant reduction of mean VAS values for DH-related pain assessed by volatile testing for both groups (p<0.001), and the assessment at the 60-day follow-up showed mean values statistically similar to those obtained at the end of treatment. Initial tactile sensitivity observed was 1.48 (2.39) for the Biosilicate and 1.4 (2.2) for the Duraphat group and at the 60-day follow-up 0.23 (0.73) and 0.15 (0.36), respectively, with significant statistical difference (p<0.002). When the reduction in tactile and volatile sensitivities between both groups was compared, no statistically significant difference was observed.

Conclusion: This study indicated that both products were able to promote an important reduction in dentin hypersensitivity with similar results within a 60-day follow-up.