1 Division of Cardiovascular Medicine, Department of Internal Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan. katsurada@jichi.ac.jp.
2 Division of Clinical Pharmacology, Department of Pharmacology, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan. katsurada@jichi.ac.jp.
3 Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE, USA.