Perceived benefit of antibiotics irrigation before pharyngeal repair of severe cut-throat injuries

Injury. 2024 Jun;55(6):111542. doi: 10.1016/j.injury.2024.111542. Epub 2024 Apr 4.

Abstract

Introduction: Wound irrigation has been employed as an important surgical step to remove bacteria, devitalized tissues, and foreign bodies from surgical sites to prevent infection and confer to the wound maximum potential of healing.

Method: A prospective study was conducted at Federal Medical Centre, Gusau, between January 2019- August 2023 to assess the benefit of antibiotics as additives in irrigation of dirty wounds. Seven (7) patients in total were presented with severe cut-throat injuries that require laryngopharyngoplasty. A combination of injection ciprofloxacin and metronidazole were used as additives into 1 L of normal saline, low pressure irrigation was done using 20mls syringe fitted to a broken needle or canular. Dysphagia Outcome and Severity Scale (DOSS) was used to assess return of pharyngeal function.

Result: The mean time of presentation of the patients was 34 ± 29 h (µ ± standard deviation) and a range of 6-72 h. The mean repair time was 58.3 ± 38.4 h with a range of 24-120 h. Most of the patients (85.7 %) had dysphagia outcome and severity scale of level 5 when per oral feeding was started with steady progress until discharge day.

Conclusion: Wound irrigation is one of the most crucial steps in treating severe cut-throat injuries. Based on our experience, adding antibiotics to the irrigant has shown potential in the control of local infection, particularly where patients present late.

Keywords: Antibiotics; Irrigation; Severe cut-throat.

MeSH terms

  • Adult
  • Anti-Bacterial Agents* / administration & dosage
  • Anti-Bacterial Agents* / therapeutic use
  • Ciprofloxacin / administration & dosage
  • Ciprofloxacin / therapeutic use
  • Deglutition Disorders
  • Female
  • Humans
  • Male
  • Metronidazole / therapeutic use
  • Middle Aged
  • Pharynx* / injuries
  • Prospective Studies
  • Surgical Wound Infection / prevention & control
  • Therapeutic Irrigation* / methods
  • Treatment Outcome
  • Wound Healing
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Ciprofloxacin
  • Metronidazole