Preparation, structural characteristics and pharmacological activity of polysaccharides from Polygala tenuifolia: A review

Carbohydr Res. 2024 May:539:109117. doi: 10.1016/j.carres.2024.109117. Epub 2024 Apr 10.

Abstract

Polygala tenuifolia is a traditional Chinese medicine with a long history of application, with the efficacy of suppressing cough, calming asthma, tranquilizing the mind, and benefiting the intellect. It is classified as a top-quality medicine in Shennong's Classic of Materia Medica. Polysaccharide is an important active ingredient in Polygala tenuifolia, which consists of several monosaccharides, including Ara, Gal, Glc, and so on. In this review, the preparation methods, structural characteristics, and biological activities of polysaccharides from Polygala tenuifolia are summarized, and the problems in the current studies are discussed to support further research, development, and utilization.

Keywords: Biological activity; Polygala tenuifolia; Polysaccharide; Preparation methods; Structural characteristics.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Polygala* / chemistry
  • Polysaccharides* / chemistry
  • Polysaccharides* / isolation & purification
  • Polysaccharides* / pharmacology

Substances

  • Polysaccharides