Chronic stress, social support, and symptoms at midlife. Is there a buffering effect?

Am J Biol Anthropol. 2024 Jun;184(2):e24936. doi: 10.1002/ajpa.24936. Epub 2024 Apr 16.

Abstract

Objectives: This study was designed to examine associations among measures of stress, social support, and symptoms at midlife. Specifically, the study examined whether support buffered against the negative effects of stress on severity of symptoms grouped via factor analyses into emotional instability, vaso-somatic symptoms, mood disturbances, and aches and pains.

Methods: We used cross-sectional data from n = 119 women aged 40-55 in Nagaland, India. Midlife symptoms were measured with the help of questionnaires, and factor analysis was used to identify latent factors. Stress and social support were measured by Perceived Stress Scale and Multidimensional Scale of Perceived Social Support, respectively. Chronic stress was measured by fingernail cortisol.

Results: After adjusting for menopausal status, tobacco use, body mass index, and socioeconomic status, cortisol level was positively associated with emotional instability (p < 0.01), vaso-somatic symptom score (p < 0.05), and total symptoms at midlife (p < 0.05). Familial support was negatively associated with emotional instability (p < 0.05) and total symptoms at midlife (p < 0.05). However, no significant associations were observed with spousal or friend support. Although no significant interactions between stress, social support, and symptoms at midlife were observed, spousal support when stratified as high and low support using the means, perceived stress and vaso-somatic symptoms indicated an interaction.

Conclusion: Cortisol level and support from family were independently associated with symptoms at midlife. The study highlights the importance of family ties and support for navigating the stressors of everyday life among women in Nagaland.

Keywords: Nagaland; fingernail cortisol; social support; stress; symptoms at midlife.

MeSH terms

  • Adult
  • Cross-Sectional Studies
  • Female
  • Humans
  • Hydrocortisone / analysis
  • Hydrocortisone / metabolism
  • India / epidemiology
  • Middle Aged
  • Social Support*
  • Stress, Psychological* / psychology