Cutaneous mucormycosis with suspected dissemination in a patient with metastatic adrenocortical carcinoma

Nakul Dar; Abigail Wills; Scott Berg; Sarah E Gradecki; Thomas G Cropley; Darren Guffey

doi:10.1016/j.mmcr.2024.100646

Cutaneous mucormycosis with suspected dissemination in a patient with metastatic adrenocortical carcinoma

Med Mycol Case Rep. 2024 Apr 2:44:100646. doi: 10.1016/j.mmcr.2024.100646. eCollection 2024 Jun.

Authors

Nakul Dar¹, Abigail Wills², Scott Berg², Sarah E Gradecki³, Thomas G Cropley², Darren Guffey²

Affiliations

¹ School of Medicine, University of Virginia, Charlottesville, VA, 22908, USA.
² Department of Dermatology, University of Virginia, Charlottesville, VA, 22908, USA.
³ Department of Pathology, University of Virginia, Charlottesville, VA, 22908, USA.

Abstract

Mucormycosis is a frequently lethal fungal infection that most commonly affects patients with poorly controlled diabetes or other immunosuppressed states. We report the case of a suspected disseminated Rhizopus infection in a patient who was pursuing naturopathic treatment including mud baths for metastatic adrenocortical carcinoma. He was empirically treated with liposomal amphotericin B but opted to stop treatment following multiorgan failure. The patient passed away on the tenth day of his hospital admission.

Keywords: Immunocompetent; Metastatic adrenocortical carcinoma; Mucormycosis; Rhizopus; Zygomycosis.

Publication types

Case Reports