Percutaneous kyphoplasty with or without posterior pedicle screw fixation for the management of severe osteoporotic vertebral compression fractures with nonunion

J Orthop Surg Res. 2024 Apr 15;19(1):240. doi: 10.1186/s13018-024-04714-y.

Abstract

Objective: To assess the radiographic outcomes, clinical outcomes and complications of percutaneous kyphoplasty (PKP) with and without posterior pedicle screw fixation (PPSF) in the treatment of severe osteoporotic vertebral compression fractures (sOVCF) with nonunion.

Methods: This study involved 51 patients with sOVCF with nonunion who underwent PKP or PPSF + KP. The operation time, intraoperative blood loss, volume of injected bone cement, operation costs and hospital stays were all recorded. In addition, the Visual Analogue Scale (VAS) and the Oswestry Disability Index (ODI) were assessed separately for each patient before and after surgery.

Results: Compared with the PPSF + KP group, the PKP group had shorter operation time, less intraoperative blood loss, shorter hospital stays and fewer operation costs. However, cobb's angle improvement (13.4 ± 4.3° vs. 21.4 ± 5.3°), VWR improvement ratio (30.4 ± 11.5% vs. 52.8 ± 12.7%), HA (34.9 ± 9.0% vs. 63.7 ± 7.6%) and HM (28.4 ± 11.2% vs. 49.6 ± 7.7%) improvement ratio were all higher in PPSF + KP group than that in PKP group. In addition, the ODI index and VAS score in both groups were significantly decreased at the postoperative and final follow-up. PKP group's postoperative VAS score was significantly lower than that in PPSF + KP group, but there was no statistically significant difference in VAS score at the last follow-up.

Conclusion: PKP and PPSF + KP can both effectively relieve the pain associated with sOVCF with nonunion. PPSF + KP can achieve more satisfactory vertebral reduction effects compared to PKP. However, PKP was less invasive and it has more advantages in shortening operation time and hospital stay, as well as decreasing intraoperative blood loss and operation costs.

Keywords: Fracture nonunion; Osteoporosis; Percutaneous kyphoplasty; Posterior pedicle screw fixation; Severe osteoporotic vertebral compression fracture.

MeSH terms

  • Blood Loss, Surgical
  • Bone Cements / therapeutic use
  • Fractures, Compression* / diagnostic imaging
  • Fractures, Compression* / drug therapy
  • Fractures, Compression* / surgery
  • Humans
  • Kyphoplasty*
  • Osteoporotic Fractures* / diagnostic imaging
  • Osteoporotic Fractures* / drug therapy
  • Osteoporotic Fractures* / surgery
  • Pedicle Screws*
  • Retrospective Studies
  • Spinal Fractures* / diagnostic imaging
  • Spinal Fractures* / drug therapy
  • Spinal Fractures* / surgery
  • Treatment Outcome

Substances

  • Bone Cements