Draft Genome Sequence of Candida saopaulonensis from a Very Premature Infant with Sepsis

Ya-Ting Ning; Rong-Chen Dai; Zheng-Yu Luo; Meng Xiao; Yingchun Xu; Qun Yan; Li Zhang

doi:10.1007/s11046-024-00838-1

Draft Genome Sequence of Candida saopaulonensis from a Very Premature Infant with Sepsis

Mycopathologia. 2024 Apr 15;189(3):32. doi: 10.1007/s11046-024-00838-1.

Authors

Ya-Ting Ning^#^{1

2}, Rong-Chen Dai^#^{1

2}, Zheng-Yu Luo^{1

2}, Meng Xiao^{1

2}, Yingchun Xu^{1

2}, Qun Yan³, Li Zhang^{4

5}

Affiliations

¹ Department of Laboratory Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China.
² Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Beijing, 100730, China.
³ Department of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, 410008, China. yanqun@csu.edu.cn.
⁴ Department of Laboratory Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China. zhanglipumchlab@163.com.
⁵ Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Beijing, 100730, China. zhanglipumchlab@163.com.

^# Contributed equally.

Abstract

The rare fungus Candida saopaulonensis has never been reported to be associated with human infection. We report the draft genome sequence of the first clinical isolate of C. saopaulonensis, which was isolated from a very premature infant with sepsis. This is the first genome assembly reaching the near-complete chromosomal level with structural annotation for this species, opening up avenues for exploring evolutionary patterns and genetic mechanisms of pathogenesis.

Keywords: Candida saopaulonensis; Annotation; Clinical case; Fungi; Genome assembly; Whole genome sequencing.

MeSH terms

Candida* / genetics
Genome, Fungal
Humans
Infant, Newborn
Infant, Premature
Sepsis*

Abstract

MeSH terms

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