Stability of the Motor Optimality Score Revised (MOS-R) in medically complex infants

Colleen Peyton; David Aaby; Ryan Millman; Sarah Rodriguez; Lynn Boswell; Deborah Gaebler-Spira; Raye-Ann de Regnier; Vanessa Maziero Barbosa; Theresa Sukal-Moulton

doi:10.1016/j.earlhumdev.2024.106008

Stability of the Motor Optimality Score Revised (MOS-R) in medically complex infants

Early Hum Dev. 2024 May:192:106008. doi: 10.1016/j.earlhumdev.2024.106008. Epub 2024 Apr 10.

Authors

Colleen Peyton¹, David Aaby², Ryan Millman³, Sarah Rodriguez⁴, Lynn Boswell⁵, Deborah Gaebler-Spira⁶, Raye-Ann de Regnier⁷, Vanessa Maziero Barbosa⁸, Theresa Sukal-Moulton⁹

Affiliations

¹ Department of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, 645 N Michigan Ave, Suite 1100, Chicago, IL, 60611, USA; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Electronic address: colleen.peyton1@northwestern.edu.
² Department of Research Services, Northwestern University Libraries, Chicago, IL, USA; Department of Preventive Medicine, Northwestern University, Chicago, IL, USA.
³ Department of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, 645 N Michigan Ave, Suite 1100, Chicago, IL, 60611, USA.
⁴ Department of Ophthalmology and Visual Science, University of Chicago, Chicago, IL, USA.
⁵ Ann and Robert H Lurie Children's Hospital, Chicago, IL, USA.
⁶ Ann and Robert H Lurie Children's Hospital, Chicago, IL, USA; Shirley Ryan AbilityLab, Chicago, IL, USA; Department of Physical Medicine and Rehabilitation, Feinberg School of Medicine, Northwestern University.
⁷ Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; Ann and Robert H Lurie Children's Hospital, Chicago, IL, USA.
⁸ University of Illinois Health, Chicago, IL, USA.
⁹ Department of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, 645 N Michigan Ave, Suite 1100, Chicago, IL, 60611, USA; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

PMID: 38615539
DOI: 10.1016/j.earlhumdev.2024.106008

Abstract

Background: The Motor Optimality Score-Revised (MOS-R) is a clinical test of infant spontaneous movement at 3-5 months of age and has been associated with neurodevelopmental outcomes in infants with medical complexity. However the stability of the MOS-R tested at different developmental ages is not yet known.

Aim: To determine if the repeated scoring of the MOS-R remained consistent when tested at two developmental ages in young infants.

Study design: In this prospective cohort study, infants were tested twice with the MOS-R between 12 and 13 weeks corrected age (CA) and 14-16 weeks CA. Bland Altman Plots were used to calculate agreement between the scores. Infants were grouped as having higher or lower medical complexity. MOS-R threshold scores were analyzed to assess changes over time within each group using Fisher's exact test.

Subjects: 85 infants with history of hospitalization in a neonatal intensive care unit (NICU).

Results: The MOS-R scores had a high agreement with negligible bias (0.058) between timepoints (95 % CI -1.10, 1.22). Using a MOS-R cut point of 19, infants with higher medical complexity were more likely to change groups between timepoints than infants with lower medical complexity (p = 0.008), but this was not significantly different using cut points of 20 or 21.

Conclusion: The MOS-R scores were stable when measured repeatedly in infants who were hospitalized in a NICU. Infants with high medical complexity had less stable MOS-R scores using certain cut points than infants with lower medical complexity.

Keywords: General Movement Assessment; Motor Optimality Score Revised; NICU follow-up.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Child Development*
Female
Humans
Infant
Infant, Newborn
Male
Motor Skills
Prospective Studies