Consensus of the Brazilian association of hematology, hemotherapy and cellular therapy on patient blood management: Anemia tolerance

Hematol Transfus Cell Ther. 2024 Apr;46 Suppl 1(Suppl 1):S67-S71. doi: 10.1016/j.htct.2024.02.018. Epub 2024 Mar 21.

Abstract

Anemia is a pathological condition in which the hemoglobin and red blood cell mass decrease; it is mainly defined by the concentration of hemoglobin in the blood. The World Health Organization guidelines establish specific values to define anemia in different population groups. Early detection of anemia can also be a valuable indicator of underlying medical conditions. Clinical studies have explored the relationship between perioperative anemia and morbidity, highlighting the need for more judicious therapeutic strategies, such as the use of Patient Blood Management, which aims to prevent and treat anemia in a personalized and effective way. Patient Blood Management emerges as a promising approach to dealing with anemia, recognizing that its correction through transfusion always carries risks and that personalized prevention and treatment can offer better outcomes for patients.

Keywords: Iron deficiency anemia; Isovolemic anemia; Morbidity and mortality; Tissue hypoxia; Transfusion thresholds.