Oral verrucous xanthoma with oral lichen planus: a case report

Hua Xi Kou Qiang Yi Xue Za Zhi. 2023 Feb 1;41(1):104-109. doi: 10.7518/hxkq.2023.01.014.
[Article in English, Chinese]

Abstract
in English, Chinese

Verrucous xanthoma is a rare benign muco-cutaneous lesion, whereas oral lichen planus is a chronic inflammatory disease relatively common in the clinical setting. Verrucous xanthoma and oral lichen planus can reportedly coexist according to foreign literature. Owing to the low incidence of verrucous xanthoma and the rarity of co-occurrence of these two diseases, the mechanism underlying the co-occurrence of the two diseases remains inconclusive. In this work, a case of oral verrucous xanthoma complicated with oral lichen planus was reported. Related literature was reviewed to discuss the clinical classification, pathological classification, and possible pathogenesis of the two diseases.

疣状黄瘤是一种罕见的良性黏膜皮肤病变，而口腔扁平苔藓则是口腔门诊中较为常见的一种慢性炎症性疾病。国外已有文献报道，疣状黄瘤与口腔扁平苔藓可以存在伴发现象。由于疣状黄瘤的低发病率，两病共存的情况较为罕见，目前，对于两种疾病伴发的内在机制尚无定论。本文报道了1例口腔疣状黄瘤合并口腔扁平苔藓的临床病例，并回顾相关文献，探讨两种疾病伴发的临床分类、病理分型及可能的发病机制。.

Keywords: oral lichen planus; pathogenesis; pathological classification; verrucous xanthoma.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Verrucous* / complications
  • Carcinoma, Verrucous* / pathology
  • Humans
  • Lichen Planus* / complications
  • Lichen Planus* / pathology
  • Lichen Planus, Oral*
  • Skin
  • Xanthomatosis* / complications
  • Xanthomatosis* / pathology

Grants and funding

[基金项目] 山东省重点研发计划（公益类）（2017GSF218063）